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Literature Chain Paper #1
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Literature Chain Paper #1 In the report, “Coupled Transcription and Translation within Nuclei of Mammalian Cells” by Francisco J. Iborra et al., Iborra and his researchers proposed the idea that translation, which normally goes on solely in the cytoplasm, can occur in the nucleus of a eukaryotic cell. By using the protein precursor lysine with three different tags, ³H, biotin, and BODIPY, they were able to label polypeptides that were created inside the cell’s nucleus. They found that the nucleus contained the machinery to commence translation, although only a fraction of the ribosomes were present inside the nuclear membrane. What is suggested and tested is that some ribosomes are left in the nucleus when they are being exported to the cytoplasm, and the ones left behind become active in translation.
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Paper Information
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Title: Literature Chain Paper #1
Words: 524
Rating: None
Pages: 2.1
submitted by: bartropolis
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