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serotonin
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SEROTONIN
Chris McGorman
CHE 112
April 28, 2003
Introduction
Serotonin is an extremely important chemical in the human body. ... The most successful form of antidepressants, SSRIs, focus on keeping high levels of serotonin in the synapses between neurons in the brain. ...
In this paper I will attempt to explain the role of serotonin in depression, and the effects of antidepressants on serotonin production and levels in the human brain. ...
General Background
Serotonin:
Chemical Name: 5-hydroxytryptamine, or 5-HT
Empirical Formula: C10H12N2O
Molecular Weight: 176. ... 5°C
Serotonin is involved with neurological functions such as sleep, appetite, sensory perception, temperature regulation, pain suppression, and mood. ... It has been estimated that an adult human contains about 5 to 10 mg of serotonin, 90% of which is in the intestine and the rest in blood platelets and the brain (Schimelpfening, 1).
Serotonin in the brain functions as a neurotransmitter. ... Packets of serotonin molecules are released from the end of the axon into the synapse (the space between neurons). These molecules may then be taken up by serotonin receptors of the dendrite of the next neuron, where they pass along their chemical message. ...
Serotonin is synthesized in the body from the amino acid, tryptophan
(C11H12N2O2). Tryptophan reacts with the enzyme, tryptophan hydroxylase, to give
serotonin. Foods such as turkey and milk contain tryptophan and can therefore indirectly increase serotonin levels in the brain.
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Paper Information
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Title: serotonin
Words: 1085 Rating: None Pages: 4.3 submitted by: chrism610
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